San Francisco’s Chinatown, the oldest and one of the largest in North America, is a vibrant cultural hub that offers visitors a glimpse into the rich traditions, history, and flavors of Chinese culture. Spanning 24 blocks and filled with iconic landmarks, bustling markets, and authentic eateries, Chinatown is a must-visit destination in San Francisco. This guide provides an in-depth look at how to explore the neighborhood through a san francisco chinatown tour guide.San Francisco’s Chinatown was established in the mid-19th century, primarily by Chinese immigrants who came during the California Gold Rush and to work on the Transcontinental Railroad.